Label-Free Biosensor Detection of Endocrine Disrupting Compounds Using Engineered Estrogen Receptors
نویسندگان
چکیده
منابع مشابه
Label-Free Biosensor Detection of Endocrine Disrupting Compounds Using Engineered Estrogen Receptors
Endocrine Disrupting Compounds (EDCs) are chemical substances shown to interfere with endogenous hormones affecting the endocrine, immune and nervous systems of mammals. EDCs are the causative agents of diseases including reproductive disorders and cancers. This highlights the urgency to develop fast and sensitive methods to detect EDCs, which are detrimental even at very low concentrations. In...
متن کاملBiosensor Array for Label-Free Biomolecular Detection
Biosensors are one of the fundamental detection platforms in biotechnology. They take advantage of unique biomolecular interactions to capture and detect specific analytes on a surface. The detection versatility of biosensors has always been their key advantage and it has been demonstrated that they can detect almost any analyte such as DNA, proteins, metabolites, and even micro-organisms. Howe...
متن کاملEndocrine Disrupting Chemicals: Interaction with Estrogen Receptors and in vitro Assessment of Endocrine Activity Potential
University of Konstanz and for coaching me through the project. Thanks to the Haematox group for the scientific but also personal support: you are not only colleagues but really good friends! Thanks to Dr. Michele Reni for the constant presence, for the optimism and for making endurable the therapy. Finally, this work is dedicated to the most important people in my life: mamma, papa' and Tommaso.
متن کاملFungal Laccases Degradation of Endocrine Disrupting Compounds
Over the past decades, water pollution by trace organic compounds (ng/L) has become one of the key environmental issues in developed countries. This is the case of the emerging contaminants called endocrine disrupting compounds (EDCs). EDCs are a new class of environmental pollutants able to mimic or antagonize the effects of endogenous hormones, and are recently drawing scientific and public a...
متن کاملEndocrine Disrupting Compounds – Problems and Challenges
In this chapter, information about some of the estrogenic compounds and their environmental fate and biological influence can be found. Special attention is paid to the review of the analytical approaches used at the stages of detection and determi‐ nation of Endocrine Disrupting Compounds (EDCs) in the environmental samples. Also, a brief characterization of both cellular and non-cellular bioa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biosensors
سال: 2017
ISSN: 2079-6374
DOI: 10.3390/bios8010001